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Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress

The aim of this study was to investigate the role of cytochrome P450-2E1 (CYP2E1) in aging-dependent kidney damage since it is poorly understood. Young (7 weeks) and aged female (16–17 months old) wild-type (WT) and Cyp2e1-null mice were used. Kidney histology showed that aged WT mice exhibited typi...

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Abdelmegeed, Mohamed A., Choi, Youngshim, Ha, Seung-Kwoon, Song, Byoung-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656532/
https://ncbi.nlm.nih.gov/pubmed/28843596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2017.08.022
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