Prevalence and Clinical Impacts of HIV-1 Intersubtype Recombinants in Uganda Revealed by Near-Full-Genome Population and Deep Sequencing Approaches

OBJECTIVES: To estimate prevalence, examine time trends, and test for clinical correlates and outcomes associated with HIV-1 intersubtype recombination under a full-genome sequencing context in a rural community in Mbarara, Uganda, where HIV-1 subtypes A1 and D co-circulate. METHODS: Near-full-genom...

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Publicat a:AIDS
Autors principals: Lee, Guinevere Q., Bangsberg, David R., Mo, Theresa, Lachowski, Chris, Brumme, Chanson J., Zhang, Wendy, Lima, Viviane D., Boum, Yap, Mwebesa, Bosco Bwana, Muzoora, Conrad, Andia, Iren, Mbalibulha, Yona, Kembabazi, Annet, Carroll, Ryan, Siedner, Mark J., Haberer, Jessica E., Mocello, A. Rain, Kigozi, Simone H., Hunt, Peter W., Martin, Jeffrey N., Harrigan, P. Richard
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656522/
https://ncbi.nlm.nih.gov/pubmed/28832407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001619
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