Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer

The lysyl oxidase-like protein LOXL2 has been suggested to contribute to tumor progression and metastasis, but in vivo evidence has been lacking. Here we provide functional evidence that LOXL2 is a key driver of breast cancer metastasis in two conditional transgenic mouse models of PyMT-induced brea...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Salvador, Fernando, Martin, Alberto, López-Menéndez, Celia, Moreno-Bueno, Gema, Santos, Vanesa, Vázquez-Naharro, Alberto, Santamaria, Patricia G., Morales, Saleta, Dubus, Pierre R., Muinelo-Romay, Laura, López-López, Rafael, Tung, Jason C., Weaver, Valerie M., Portillo, Francisco, Cano, Amparo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656180/
https://ncbi.nlm.nih.gov/pubmed/28720577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3152
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