Can Sevoflurane Induce Micronuclei Formation in Nasal Epithelial Cells of Adult Patients?

OBJECTIVE: Volatile anaesthetics can inhibit the bronchociliary clearence in a dose- and time-dependend way. Moreover, they can have potential mutagenic/carcinogenic effects under chronic exposure. A genotoxicity test -micronuclei assay- was carried out in nasal epithelial cells to analyze the genot...

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Vydáno v:Turk J Anaesthesiol Reanim
Hlavní autoři: Kesimci, Elvin, Çoşkun, Erdem, Uğur, Gökçer, Müderris, Togay, İzdeş, Seval, Karahalil, Bensu
Médium: Artigo
Jazyk:Inglês
Vydáno: Turkish Anaesthesiology and Intensive Care Society 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656160/
https://ncbi.nlm.nih.gov/pubmed/29114410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/TJAR.2017.09475
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