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Ezetimibe Increases Endogenous Cholesterol Excretion in Humans

OBJECTIVE: Ezetimibe improves cardiovascular outcomes when added to optimum statin treatment. It lowers LDL cholesterol and percent intestinal cholesterol absorption, but the exact cardioprotective mechanism is unknown. We tested the hypothesis that the dominant effect of ezetimibe is to increase th...

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Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Lin, Xiaobo, Racette, Susan B, Ma, Lina, Wallendorf, Michael, Ostlund, Richard E
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656065/
https://ncbi.nlm.nih.gov/pubmed/28279967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309119
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