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Host sphingosine kinase 1 worsens pancreatic cancer peritoneal carcinomatosis
BACKGROUND: There are no effective treatments for pancreatic cancer peritoneal carcinomatosis (PC) or cancer dissemination in abdominal cavity. Sphingosine-1-phosphate (S1P), a bioactive lipid mediator produced by sphingosine kinases (SphK1 and SphK2), plays critical roles in cancer progression. We...
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Publicado no: | J Surg Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656061/ https://ncbi.nlm.nih.gov/pubmed/27664902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2016.05.034 |
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