Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants

BACKGROUND: The pathogenesis of acute-on-chronic liver failure (ACLF) in chronic hepatitis B (CHB) is not well understood. The aim of this study was to investigate whether there is an association between HBV polymerase (P)/overlapping surface (S) gene and basal core promoter (BCP)/precore (PC) varia...

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Publicado en:Virol J
Autores principales: Gao, Shan, Joshi, Shivali S., Osiowy, Carla, Chen, Y., Coffin, Carla S., Duan, Z-P.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655973/
https://ncbi.nlm.nih.gov/pubmed/29065883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0870-x
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