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The Repression of Atoh1 by Neurogenin1 during Inner Ear Development
Atonal homolog 1 (Atoh1) and Neurogenin1 (Neurog1) are basic Helix-Loop-Helix (bHLH) transcription factors crucial for the generation of hair cells (HCs) and neurons in the inner ear. Both genes are induced early in development, but the expression of Atoh1 is counteracted by Neurog1. As a result, HC...
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| Publicado no: | Front Mol Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655970/ https://ncbi.nlm.nih.gov/pubmed/29104531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00321 |
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