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Gastrointestinal toxicity among patients taking selective COX‐2 inhibitors or conventional NSAIDs, alone or combined with proton pump inhibitors: a case–control study

PURPOSE: To assess the risk of gastrointestinal perforation, ulcers, or bleeding (PUB) associated with the use of conventional nonsteroidal anti‐inflammatory drugs (NSAIDs) with proton pump inhibitors (PPIs) and selective COX‐2 inhibitors, with or without PPIs compared with conventional NSAIDs. METH...

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Detalhes bibliográficos
Publicado no:Pharmacoepidemiol Drug Saf
Main Authors: Bakhriansyah, Mohammad, Souverein, Patrick C., de Boer, Anthonius, Klungel, Olaf H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655916/
https://ncbi.nlm.nih.gov/pubmed/28370857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.4183
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