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The rationale and design of TransCon Growth Hormone for the treatment of growth hormone deficiency

The fundamental challenge of developing a long-acting growth hormone (LAGH) is to create a more convenient growth hormone (GH) dosing profile while retaining the excellent safety, efficacy and tolerability of daily GH. With GH receptors on virtually all cells, replacement therapy should achieve the...

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Bibliographic Details
Published in:Endocr Connect
Main Authors: Sprogøe, Kennett, Mortensen, Eva, Karpf, David B, Leff, Jonathan A
Format: Artigo
Language:Inglês
Published: Bioscientifica Ltd 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655688/
https://ncbi.nlm.nih.gov/pubmed/28947559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-17-0203
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