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MGMT and MSH6 immunoexpression for functioning pituitary macroadenomas

PURPOSE: Knowledge of biological behavior is crucial for clinical management of functioning pituitary macroadenomas. For recurrent cases unresponsive to standard treatment, temozolomide (TMZ) has been used as a therapeutic alternative. MGMT (O6-methyl-guanine-DNA methyltransferase) and MSH6 (mutS ho...

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Detalhes bibliográficos
Publicado no:Pituitary
Main Authors: Micko, Alexander S. G., Wöhrer, Adelheid, Höftberger, Romana, Vila, Greisa, Marosi, Christine, Knosp, Engelbert, Wolfsberger, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655586/
https://ncbi.nlm.nih.gov/pubmed/28900805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11102-017-0829-3
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