Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation

The mitotic spindle is composed of dynamic microtubules and associated proteins that together direct chromosome movement during mitosis. The spindle plays a vital role in accurate chromosome segregation fidelity and is a therapeutic target in cancer. Nevertheless, the molecular mechanisms by which m...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Mills, Christine A., Suzuki, Aussie, Arceci, Anthony, Mo, Jin Yao, Duncan, Alex, Salmon, Edward D., Emanuele, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655498/
https://ncbi.nlm.nih.gov/pubmed/28900032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.796045
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