Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients

Tacrolimus (FK506) and cyclosporine A (CsA) are widely used to protect graft function after renal transplantation. The aim of the present study is to determine whether the single nucleotide polymorphism of CYP3A5 is a predictive index of FK506 dose requirement, and also the selection yardstick of FK...

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Pubblicato in:Oncotarget
Autori principali: Qu, Lihui, Lu, Yingying, Ying, Meike, Li, Bingjue, Weng, Chunhua, Xie, Zhoutao, Liang, Ludan, Lin, Chuan, Yang, Xian, Feng, Shi, Wang, Yucheng, Shen, Xiujin, Zhou, Qin, Chen, Ying, Chen, Zhimin, Wu, Jianyong, Lin, Weiqiang, Shen, Yi, Qin, Jing, Xu, Hang, Xu, Feng, Wang, Junwen, Chen, Jianghua, Jiang, Hong, Huang, Hongfeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Clinical Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655282/
https://ncbi.nlm.nih.gov/pubmed/29113387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18150
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