Real-Time PCR Targeting the penA Mosaic XXXIV Type for Prediction of Extended-Spectrum-Cephalosporin Susceptibility in Clinical Neisseria gonorrhoeae Isolates

Neisseria gonorrhoeae isolates with decreased susceptibility to extended-spectrum cephalosporins (ESCs) are increasing. We developed an assay to predict N. gonorrhoeae susceptibility to ESCs by targeting penA mosaic XXXIV, an allele prevalent among U.S. isolates with elevated ESC MICs. The assay was...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Wong, L. K., Hemarajata, P., Soge, O. O., Humphries, R. M., Klausner, J. D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Epidemiology and Surveillance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655115/
https://ncbi.nlm.nih.gov/pubmed/28848021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01339-17
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