Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development

Despite recent successful control efforts, malaria remains a leading global health burden. Alarmingly, resistance to current antimalarials is increasing and the development of new drug families is needed to maintain malaria control. Current antimalarials target the intraerythrocytic developmental st...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Boyle, Michelle J., Skidmore, Mark, Dickerman, Benjamin, Cooper, Lynsay, Devlin, Anthony, Yates, Edwin, Horrocks, Paul, Freeman, Craig, Chai, Wengang, Beeson, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655105/
https://ncbi.nlm.nih.gov/pubmed/28893781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00709-17
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