Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development

Despite recent successful control efforts, malaria remains a leading global health burden. Alarmingly, resistance to current antimalarials is increasing and the development of new drug families is needed to maintain malaria control. Current antimalarials target the intraerythrocytic developmental st...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Boyle, Michelle J., Skidmore, Mark, Dickerman, Benjamin, Cooper, Lynsay, Devlin, Anthony, Yates, Edwin, Horrocks, Paul, Freeman, Craig, Chai, Wengang, Beeson, James G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655105/
https://ncbi.nlm.nih.gov/pubmed/28893781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00709-17
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