Using Population Pharmacokinetic Modeling and Monte Carlo Simulations To Determine whether Standard Doses of Piperacillin in Piperacillin-Tazobactam Regimens Are Adequate for the Management of Febrile Neutropenia

Changes in the pharmacokinetics of piperacillin in febrile neutropenic patients have been reported to result in suboptimal exposures. This study aimed to develop a population pharmacokinetic model for piperacillin and perform dosing simulation to describe optimal dosing regimens for hematological ma...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L., Roberts, Jason A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655099/
https://ncbi.nlm.nih.gov/pubmed/28807922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00311-17
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker