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Efficacy of Humanized Exposures of Cefiderocol (S-649266) against a Diverse Population of Gram-Negative Bacteria in a Murine Thigh Infection Model

Cefiderocol (S-649266) is a novel siderophore cephalosporin with potent in vitro activity against clinically encountered multidrug-resistant (MDR) Gram-negative isolates; however, its spectrum of antibacterial activity against these difficult-to-treat isolates remains to be fully explored in vivo. H...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Monogue, Marguerite L., Tsuji, Masakatsu, Yamano, Yoshinori, Echols, Roger, Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655050/
https://ncbi.nlm.nih.gov/pubmed/28848004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01022-17
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