Endothelial Regulator of Calcineurin 1 Promotes Barrier Integrity and Modulates Histamine-Induced Barrier Dysfunction in Anaphylaxis

Anaphylaxis, the most serious and life-threatening allergic reaction, produces the release of inflammatory mediators by mast cells and basophils. Regulator of calcineurin 1 (Rcan1) is a negative regulator of mast-cell degranulation. The action of mediators leads to vasodilation and an increase in va...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ballesteros-Martinez, Constanza, Mendez-Barbero, Nerea, Montalvo-Yuste, Alma, Jensen, Bettina M., Gomez-Cardenosa, Aída, Klitfod, Lotte, Garrido-Arandia, María, Alvarez-Llamas, Gloria, Pastor-Vargas, Carlos, Vivanco, Fernando, Garvey, Lene Heise, Cuesta-Herranz, Javier, Poulsen, Lars K., Esteban, Vanesa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655011/
https://ncbi.nlm.nih.gov/pubmed/29104573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01323
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