Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection

Mice deficient for granulocyte-macrophage colony-stimulating factor (GM-CSF(−/−)) are highly susceptible to infection with Mycobacterium tuberculosis, and clinical data have shown that anti-GM-CSF neutralizing antibodies can lead to increased susceptibility to tuberculosis in otherwise healthy peopl...

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Udgivet i:mBio
Main Authors: Rothchild, Alissa C., Stowell, Britni, Goyal, Girija, Nunes-Alves, Cláudio, Yang, Qianting, Papavinasasundaram, Kadamba, Sassetti, Christopher M., Dranoff, Glenn, Chen, Xinchun, Lee, Jinhee, Behar, Samuel M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654932/
https://ncbi.nlm.nih.gov/pubmed/29066547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01514-17
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