Neuronal Sirt1 Regulates Glycolysis and Mediates Resveratrol-Induced Ischemic Tolerance

BACKGROUND AND PURPOSE: Resveratrol, at least in part via Sirt1 activation, protects against cerebral ischemia when administered 2 days prior to injury. However, it remains unclear if Sirt1 activation must occur, and in which brain cell types, for the induction of neuroprotection. We hypothesized th...

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Pubblicato in:Stroke
Autori principali: Koronowski, Kevin B, Khoury, Nathalie, Saul, Isabel, Loris, Zachary B, Cohan, Charles H, Stradecki-Cohan, Holly M, Dave, Kunjan R, Young, Juan I, Perez-Pinzon, Miguel A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654689/
https://ncbi.nlm.nih.gov/pubmed/29018134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.018562
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