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Multicenter Phase I Dose Escalation Study of Hypofractionated Stereotactic Radiotherapy with Bevacizumab for Recurrent Glioblastoma and Anaplastic Astrocytoma

PURPOSE: It has been reported previously that the combination of bevacizumab with hypofractionated stereotactic re-irradiation (HFSR) with 30Gy (6GyX5 fractions) was safe and efficacious in recurrent glioblastomas and high-grade gliomas (HGG). Because most recurrences are local, developing intensifi...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Clarke, Jennifer, Neil, Elizabeth, Terziev, Robert, Gutin, Philip, Barani, Igor, Kaley, Thomas, Lassman, Andrew B., Chan, Timothy A., Yamada, Josh, DeAngelis, Lisa, Ballangrud, Ase, Young, Robert, Panageas, Katherine S., Beal, Kathryn, Omuro, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654655/
https://ncbi.nlm.nih.gov/pubmed/28870792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2017.06.2466
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