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Endosomal traffic jams represent a pathogenic hub and therapeutic target in Alzheimer’s disease
While clues have existed that endosomal trafficking is associated with Alzheimer’s disease (AD), whether it plays a central role in the disease and if so how has remained unknown. Here we rely on recent genetic and cellular findings to construct a model proposing that traffic jams in the early endos...
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| Опубликовано в: : | Trends Neurosci |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654621/ https://ncbi.nlm.nih.gov/pubmed/28962801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2017.08.003 |
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