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Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome

BACKGROUND: Adenosine to inosine (A-to-I) RNA editing has been shown to be an essential event that plays a significant role in neuronal function, as well as innate immunity, in mammals. It requires a structure that is largely double-stranded for catalysis but little is known about what determines ed...

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Vydáno v:Genome Biol
Hlavní autoři: Daniel, Chammiran, Widmark, Albin, Rigardt, Ditte, Öhman, Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654063/
https://ncbi.nlm.nih.gov/pubmed/29061182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1324-x
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