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NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins

BACKGROUND: The major human fungal pathogen Candida albicans possesses a diploid genome, but responds to growth in challenging environments by employing chromosome aneuploidy as an adaptation mechanism. For example, we have shown that C. albicans adapts to growth on the toxic sugar l-sorbose by tran...

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Publicado en:Epigenetics Chromatin
Main Authors: Wakabayashi, Hironao, Tucker, Christopher, Bethlendy, Gabor, Kravets, Anatoliy, Welle, Stephen L., Bulger, Michael, Hayes, Jeffrey, Rustchenko, Elena
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653997/
https://ncbi.nlm.nih.gov/pubmed/29061172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0156-y
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