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Fundamental limitation of the instantaneous approximation in fold‐change detection models

The phenomenon of fold‐change detection, or scale‐invariance, is exhibited by a variety of sensory systems, in both bacterial and eukaryotic signalling pathways. It has been often remarked in the systems biology literature that certain systems whose output variables respond at a faster time scale th...

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Detalhes bibliográficos
Publicado no:IET Syst Biol
Main Authors: Skataric, Maja, Nikolaev, Evgeni V., Sontag, Eduardo D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Institution of Engineering and Technology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653975/
https://ncbi.nlm.nih.gov/pubmed/25569859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb.2014.0006
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