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Arrhythmogenic cardiomyopathy related DSG2 mutations affect desmosomal cadherin binding kinetics
Cadherins are calcium dependent adhesion proteins that establish the intercellular mechanical contact by bridging the gap to adjacent cells. Desmoglein-2 (Dsg2) is a specific cadherin of the cell-cell contact in cardiac desmosomes. Mutations in the DSG2-gene are regarded to cause arrhythmogenic (rig...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653825/ https://ncbi.nlm.nih.gov/pubmed/29062102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13737-x |
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