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DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression
Accumulation of unfolded and potentially toxic proteins in the endoplasmic reticulum (ER) activates a cell stress adaptive response, which involves a reprogramming of general gene expression. ATF4 is a master stress-induced transcription factor that orchestrates gene expression in cells treated with...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653821/ https://ncbi.nlm.nih.gov/pubmed/29062139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14262-7 |
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