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Functional expression and pharmaceutical efficacy of cardiac-specific ion channels in human embryonic stem cell-derived cardiomyocytes

Cardiomyocytes differentiated from human pluripotent stem cells provide promising tools for screening of cardiotoxic drugs. For evaluation of human pluripotent stem cell-derived cardiomyocytes for cardiotoxicity test, in the present study, human embryonic stem cells (hESCs) were differentiated to ca...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Han Sol, Yoon, Jung Won, Li, Hongliang, Jeong, Geun Ok, Park, Jin Ju, Shin, Sung Eun, Jang, Il Ho, Kim, Jae Ho, Park, Won Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653792/
https://ncbi.nlm.nih.gov/pubmed/29062050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14198-y
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