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New horizons in hypoxia signaling pathways

Investigation into the regulation of the erythropoietin gene by oxygen led to the discovery of a process of direct oxygen sensing that transduces many cellular and systemic responses to hypoxia. The oxygen-sensitive signal is generated through the catalytic action of a series of 2-oxoglutarate-depen...

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Bibliographic Details
Published in:Exp Cell Res
Main Authors: Pugh, Christopher W., Ratcliffe, Peter J.
Format: Artigo
Language:Inglês
Published: Academic Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653532/
https://ncbi.nlm.nih.gov/pubmed/28315322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.03.008
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