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Beyond ALK and ROS1: RET, NTRK, EGFR and BRAF gene rearrangements in non-small cell lung cancer

The discovery of gene rearrangements involving the receptor tyrosine kinase genes ALK and ROS1 has revolutionized management of the subset of non-small cell lung cancers characterized by these alterations. The oncogenic fusion proteins expressed in these tumors drive cancer cell growth and survival,...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Farago, Anna F., Azzoli, Christopher G.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653525/
https://ncbi.nlm.nih.gov/pubmed/29114471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2017.08.02
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