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Progesterone Receptors (PR) Mediate STAT Actions: PR and Prolactin Receptor Signaling Crosstalk in Breast Cancer Models

Estrogen is the major mitogenic stimulus of mammary gland development during puberty wherein ER signaling acts to induce abundant PR expression. PR signaling, in contrast, is the primary driver of mammary epithelial cell proliferation in adulthood. The high circulating levels of progesterone during...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Steroid Biochem Mol Biol
Prif Awduron: Leehy, Katherine A., Truong, Thu H., Mauro, Laura J., Lange, Carol A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653461/
https://ncbi.nlm.nih.gov/pubmed/28442393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.04.011
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