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Human macrophages differentiated in the presence of vitamin D(3) restrict dengue virus infection and innate responses by downregulating mannose receptor expression
BACKGROUND: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D(3) has been described as an important modulator of immun...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653353/ https://ncbi.nlm.nih.gov/pubmed/29020083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005904 |
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