Modeling Physiologic Microenvironments in Three-Dimensional Microtumors Maintains Brain Tumor Initiating Cells

Development of effective novel anti-tumor treatments will require improved in vitro models that incorporate physiologic microenvironments and maintain intratumoral heterogeneity, including tumor initiating cells. Brain tumor initiating cells (BTIC) are a target for cancer therapy, because BTICs are...

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Veröffentlicht in:J Cancer Stem Cell Res
Hauptverfasser: Gilbert, Ashley N., Walker, Kiera, Tran, Anh Nhat, Boyd, Nathaniel H., Gillespie, G. Yancey, Singh, Raj K., Hjelmeland, Anita B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653320/
https://ncbi.nlm.nih.gov/pubmed/29075651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14343/JCSCR.2017.5e1004
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