Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions

Retroviral integrases (IN) catalyze the integration of the reverse-transcribed viral DNA into the host genome, an essential process leading to virus replication. For Moloney murine leukemia virus (M-MuLV) IN, the limited solubility of the recombinant protein has restricted the development of biophys...

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Gepubliceerd in:Virology
Hoofdauteurs: Villanueva, Rodrigo A., Jonsson, Colleen B., Jones, Jennifer, Georgiadis, Millie M., Roth, Monica J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653259/
https://ncbi.nlm.nih.gov/pubmed/14599799
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