Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity

Scaffolding the calcium/calmodulin-dependent phosphatase 2B (PP2B, calcineurin) focuses and insulates termination of local second messenger responses. Conformational flexibility in regions of intrinsic disorder within A-kinase anchoring protein 79 (AKAP79) delineates PP2B access to phosphoproteins....

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Nygren, Patrick J, Mehta, Sohum, Schweppe, Devin K, Langeberg, Lorene K, Whiting, Jennifer L, Weisbrod, Chad R, Bruce, James E, Zhang, Jin, Veesler, David, Scott, John D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2017
Konular:
Biochemistry and Chemical Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653234/
https://ncbi.nlm.nih.gov/pubmed/28967377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30872
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller