Impact of prior therapies on everolimus activity: an exploratory analysis of RADIANT-4

BACKGROUND: Recently, everolimus was shown to improve median progression-free survival (PFS) by 7.1 months in patients with advanced, progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of lung or gastrointestinal (GI) tract compared with placebo (HR, 0.48; 95% CI, 0.35–0.67;...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Buzzoni, Roberto, Carnaghi, Carlo, Strosberg, Jonathan, Fazio, Nicola, Singh, Simron, Herbst, Fabian, Ridolfi, Antonia, Pavel, Marianne E, Wolin, Edward M, Valle, Juan W, Oh, Do-Youn, Yao, James C, Pommier, Rodney
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652899/
https://ncbi.nlm.nih.gov/pubmed/29081664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S142087
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