Effect of TALEN-mediated IL-6 knockout on cell proliferation, apoptosis, invasion and anti-cancer therapy in hepatocellular carcinoma (HCC-LM3) cells

PURPOSE: To determine the exact effect of Interleukin-6 (IL-6) on tumor cell proliferation, apoptosis, invasion, and anti-cancer therapy in hepatocellular carcinoma (HCC). EXPERIMENTAL DESIGN: IL-6 was disrupted by transcription activator-like effector nucleases (TALEN) in HCCLM3 cells, and was used...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhuang, Peng-Yuan, Zhang, Ke-Wei, Wang, Jian-Dong, Zhou, Xue-Ping, Liu, Ying-Bin, Quan, Zhi-Wei, Shen, Jun
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652824/
https://ncbi.nlm.nih.gov/pubmed/29100435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20946
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