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DUSP4 is associated with increased resistance against anti-HER2 therapy in breast cancer
The majority of patients develop resistance against suppression of HER2-signaling mediated by trastuzumab in HER2 positive breast cancer (BC). HER2 overexpression activates multiple signaling pathways, including the mitogen-activated protein kinase (MAPK) cascade. MAPK phosphatases (MKPs) are essent...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652774/ https://ncbi.nlm.nih.gov/pubmed/29100381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20430 |
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