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Adenovirus-mediated decorin expression induces cancer cell death through activation of p53 and mitochondrial apoptosis

Decorin (DCN) is a small leucine-rich proteoglycan that plays an important role in the regulation of apoptosis, proliferation, intercellular contact, and cell migration. Here we have investigated the detailed mechanism of apoptotic cell death induced by DCN expression. A marked increase in cytotoxic...

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Pubblicato in:Oncotarget
Autori principali: Yoon, A-Rum, Hong, JinWoo, Yun, Chae-Ok
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652734/
https://ncbi.nlm.nih.gov/pubmed/29100340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20800
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