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Paradoxical effects of (137)Cs irradiation on pharmacological stimulation of reactive oxygen species in hippocampal slices from apoE2 and apoE4 mice

In humans, apoE, which plays a role in repair, is expressed in three isoforms: E2, E3, and E4. E4 is a risk factor for age-related cognitive decline (ACD) and Alzheimer's disease (AD), particularly in women. In contrast, E2 is a protective factor for ACD and AD. E2 and E4 might also differ in t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Villasana, Laura E., Akinyeke, Tunde, Weber, Sydney, Raber, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652728/
https://ncbi.nlm.nih.gov/pubmed/29100334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20603
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