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Overexpression of SIRT6 attenuates the tumorigenicity of hepatocellular carcinoma cells

OBJECTIVE: This study aimed to explore the effects of overexpression of sirtuin 6 (SIRT6) on the tumorigenicity of hepatocellular carcinoma (HCC) cells METHODS: Stable SIRT6-overexpressed HCC cell lines were established by transfecting SIRT6 plasmid. Soft agar assay and tumor xenograft assay in nude...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Yadong, Pan, Teng, Wang, Haiyu, Li, Li, Li, Jiangmin, Zhang, Ding, Yang, Haiyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652700/
https://ncbi.nlm.nih.gov/pubmed/29100306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19297
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