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RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner

Sensitivity of cancer cells to DNA damaging chemotherapeutics is determined by DNA repair processes. Consequently, cancer cells may upregulate the expression of certain DNA repair genes as a mechanism to promote chemoresistance. Here, we report that RECQ1, a breast cancer susceptibility gene that en...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Parvathaneni, Swetha, Lu, Xing, Chaudhary, Ritu, Lal, Ashish, Madhusudan, Srinivasan, Sharma, Sudha
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652675/
https://ncbi.nlm.nih.gov/pubmed/29100281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18237
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