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Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model

INTRODUCTION: We summarise an ethically approved protocol for the development of an experimental human challenge colonisation model. Globally Bordetella pertussis is one of the leading causes of vaccine-preventable death. Many countries have replaced whole cell vaccines with acellular vaccines over...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: de Graaf, Hans, Gbesemete, Diane, Gorringe, Andrew R., Diavatopoulos, Dimitri A., Kester, Kent E., Faust, Saul N., Read, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652574/
https://ncbi.nlm.nih.gov/pubmed/29025851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-018594
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