Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland

Factor H autoantibodies can impair complement regulation, resulting in atypical hemolytic uremic syndrome, predominantly in childhood. There are no trials investigating treatment, and clinical practice is only informed by retrospective cohort analysis. Here we examined 175 children presenting with a...

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Pubblicato in:Kidney Int
Autori principali: Brocklebank, Vicky, Johnson, Sally, Sheerin, Thomas P., Marks, Stephen D., Gilbert, Rodney D., Tyerman, Kay, Kinoshita, Meredith, Awan, Atif, Kaur, Amrit, Webb, Nicholas, Hegde, Shivaram, Finlay, Eric, Fitzpatrick, Maggie, Walsh, Patrick R., Wong, Edwin K.S., Booth, Caroline, Kerecuk, Larissa, Salama, Alan D., Almond, Mike, Inward, Carol, Goodship, Timothy H., Sheerin, Neil S., Marchbank, Kevin J., Kavanagh, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652378/
https://ncbi.nlm.nih.gov/pubmed/28750931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.04.028
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