Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice

Zika virus (ZIKV) has become a global public health emergency due to its rapidly expanding range and its ability to cause severe congenital defects such as microcephaly. However, there are no FDA-approved therapies or vaccines against ZIKV infection. Through our screening of viral entry inhibitors,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Li, Chunfeng, Zhu, Xingliang, Ji, Xue, Quanquin, Natalie, Deng, Yong-Qiang, Tian, Min, Aliyari, Roghiyh, Zuo, Xiangyang, Yuan, Ling, Afridi, Shabbir Khan, Li, Xiao-Feng, Jung, Jae U., Nielsen-Saines, Karin, Qin, Frank Xiao-Feng, Qin, Cheng-Feng, Xu, Zhiheng, Cheng, Genhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652284/
https://ncbi.nlm.nih.gov/pubmed/29033372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.09.034
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