Helicobacter pylori modulates cyclooxygenase-2 and 15-hydroxy prostaglandin dehydrogenase in gastric cancer

Persistent infection with Helicobacter pylori may contribute to the carcinogenesis of gastric cancer through modulating local prostaglandin E(2) (PGE(2)) levels. Cyclooxygenase-2 (COX-2) and 15-hydroxy prostaglandin dehydrogenase (15-PGDH) are two key enzymes that regulate PGE(2) synthesis and inact...

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Udgivet i:Oncol Lett
Main Authors: Zhao, Jianqiu, Wen, Shujun, Wang, Xingfen, Zhang, Zhiguang
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652235/
https://ncbi.nlm.nih.gov/pubmed/29113180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6843
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