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LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are found in familial and idiopathic cases of Parkinson's disease (PD), but are also associated with immune-related disorders, notably Crohn's disease and leprosy. Although the physiological function of LRRK2 protein remains largel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Soc Trans
Hauptverfasser: Lee, Heyne, James, William S., Cowley, Sally A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652224/
https://ncbi.nlm.nih.gov/pubmed/28202666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160262
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