MITOCHONDRIAL CARDIOMYOPATHIES FEATURE INCREASED UPTAKE AND DIMINISHED EFFLUX OF MITOCHONDRIAL CALCIUM

Calcium (Ca(2+)) influx into the mitochondrial matrix stimulates ATP synthesis. Here, we investigate whether mitochondrial Ca(2+) transport pathways are altered in the setting of deficient mitochondrial energy synthesis, as increased matrix Ca(2+) may provide a stimulatory boost. We focused on mitoc...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Sommakia, Salah, Houlihan, Patrick R., Deane, Sadiki S., Simcox, Judith A., Torres, Natalia S., Jeong, Mi-Young, Winge, Dennis R., Villanueva, Claudio J., Chaudhuri, Dipayan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652072/
https://ncbi.nlm.nih.gov/pubmed/28962857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.09.009
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