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HIGH GLUCOSE DERIVED ENDOTHELIAL MICROPARTICLES INCREASE ACTIVE CASPASE-3 AND REDUCE MicroRNA-Let-7a EXPRESSION IN ENDOTHELIAL CELLS

The experimental aim of this study was to determine the effects of high glucose-induced endothelial microparticles (EMPs) on endothelial cell susceptibility to apoptosis. Human umbilical vein endothelial cells (HUVECs) were cultured (3(rd) passage) and plated in 6-well plates at a density of 5.0 × 1...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Bammert, Tyler D., Hijmans, Jamie G., Reiakvam, Whitney R., Levy, Ma’ayan V., Brewster, Lillian M., Goldthwaite, Zoe A., Greiner, Jared J., Stockelman, Kelly A., DeSouza, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652070/
https://ncbi.nlm.nih.gov/pubmed/28942148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.09.098
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