Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses

Although several studies have investigated the functions of influenza PA-X, the impact of different expressions of PA-X protein including full-length, truncated or PA-X deficient forms on virus replication, pathogenicity and host response remains unclear. Herein, we generated two mutated viruses exp...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Lee, Jinhwa, Yu, Hai, Li, Yonghai, Ma, Jingjiao, Lang, Yuekun, Duff, Michael, Henningson, Jamie, Liu, Qinfang, Li, Yuhao, Nagy, Abdou, Bawa, Bhupinder, Li, Zejun, Tong, Guangzhi, Richt, Juergen A., Ma, Wenjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651993/
https://ncbi.nlm.nih.gov/pubmed/28142079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.01.015
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